Which type of pipette is best for precise volume measurements at less than 1 mL?

The micropipette is specifically designed for accurately measuring and transferring small volumes of liquid, particularly those less than 1 mL. This tool operates on the principle of positive displacement and utilizes a specialized pipetting mechanism, allowing for precise volume control. Micropipettes can measure volumes ranging from fractions of a microliter up to about 1 mL, making them ideal for applications in molecular biology, biochemistry, and similar fields where precision is crucial.

In contrast, Pasteur pipettes are typically used for transferring liquids but lack the precision needed for exact measurements. They are more suited for rough, non-quantitative sampling rather than precise volumetric work. Graduated pipettes allow for measuring a range of volumes, but they are generally not as precise as micropipettes for measurements under 1 mL, particularly in low-volume scenarios. Disposable plastic transfer pipettes are designed for ease of use and convenience; however, like Pasteur pipettes, they do not provide the level of accuracy required for precise volume measurement.

Thus, the micropipette stands out as the best choice due to its design and precision capabilities for volumes less than 1 mL.